Acute pancreatitis is a common clinical emergency abdomen, which has become one of the most difficult diseases for clinicians due to its rapid onset, rapid progression and poor prognosis. With the continuous improvement of medical technology and in-depth research on acute pancreatitis, the death rate of acute pancreatitis is significantly lower than before. Today, let’s talk about the common causes of acute pancreatitis. Acute pancreatitis is a reaction in which the pancreatic enzymes secreted by the pancreas are activated to self-digest their own tissues, resulting in tissue edema, hemorrhage, and necrosis. To use a direct analogy, we all know about burns, right? Acute pancreatitis is like internal burns, like sulfuric acid and hydrochloric acid poured into the abdominal cavity causing a severe reaction. This shows that acute pancreatitis is indeed a very serious acute abdominal disease. At present, the most common causes of acute pancreatitis in China are mostly seen in bile duct stones blocking the bile ducts, excessive alcohol consumption, overeating, etc. 1, the lower part of the common bile duct stones, biliary ascaris can cause pancreatic secretion obstruction, all leading to pancreatic fluid reflux, pancreatic enzymes digestion of its own tissue induced pancreatitis. Currently this is the most common cause of acute pancreatitis in China. 2, long-term heavy drinking patients, alcohol stimulates pancreatic fluid secretion in large quantities, resulting in increased pressure in the pancreatic duct, pancreatic fluid flow into the pancreatic tissue gap causing damage to their own tissues. At the same time, alcohol can also directly damage the pancreatic alveoli and pancreatic duct epithelial tissue, resulting in pancreatic injury. 3, hyperlipidemia triglycerides can cause direct damage to the pancreatic tissue under the action of pancreatic enzymes. 4, other factors including overeating, trauma, infection, drug damage and other related factors. These are the common factors of acute pancreatitis, so we can effectively reduce the occurrence of acute pancreatitis as long as we treat gallstones, avoid alcoholism, overeating and hyperlipidemia in a timely manner.