Skin is a disease that is internal and external in nature. The external causes include whether there is humidity in the house, whether there is pollution in the environment, whether there is rain and water on the trip, whether there is sweating or wind after bathing, and so on. However, when the external environmental factors and causes are not clear and cannot be identified and inferred, we have to analyze the internal causes of the disease. This can lead to itching. Xiao Yueyuan, Department of Dermatology, Xijing Hospital Neurodermatitis has no primary skin lesions, but the above factors lead to itching and then scratching, and after scratching, the local skin is damaged and gradually keratinized and proliferated, and the parts that are scratched are mostly the parts within reach of hands, such as the typical parts of the back of the neck (the collar is easy to cause annoyance, which is called pinch collar sore in Chinese medicine), sacral tail, both elbows, forearms, back of hands, outer hip, outer calf, back of feet, etc. The itching is the result. Itching is the result of this disease, but also the cause. Emotional depression and fire, fire burning the skin and forming “hot itch”; or liver depression and spleen deficiency, dampness over time resulting in “wet itch” (the classification of itch in Chinese medicine, wind, heat, dampness, insects, poison, etc.) is the result, but the itch scratching the typical parts of the skin after the formation of neuropathic Dermatitis, this itch is the cause. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. There is such a cycle, there are two directions, one to good, one to evil, to evil: itching – scratching – severe lesions – itching aggravated – more scratching – more severe lesions, then to benign development, is itching – do not scratch (to soothe the skin or topical cream as a means to relieve itching, as long as the itch to replace the scratching behavior action with topical cream) – after treatment lesions gradually improved – itching reduced – scratching less – less scratching – lighter lesions – until the disease is cured. Therefore, it seems that “scratching” plays an important or even decisive role in the therapeutic regression of the disease, and some patients have a long course of the disease, scratching severely and forming habits that cannot be corrected, and in the long run, secondary cases of nodular itchy rash and amyloidosis are common. Therefore, the understanding of the disease as a whole, the attitude and behavior towards the disease, determines whether the wrong treatment behavior of indiscriminate medical treatment, indiscriminate use of drugs, is closely related to the regression of the disease. It is very important to match the correct treatment idea and medication with scratching or not. Patients who have neurodermatitis must tolerate not scratching, change the solution, internal treatment to remove itching or to examine the cause and use medication according to the etiology, and recommend Chinese medicine treatment.