The progression of fatty liver to non-homogeneous fatty liver is generally considered to be a sign that the patient’s fatty liver is on the mend. A non-homogeneous fatty liver is a type of fatty liver also known as a localized fatty liver or a liver with restricted fatty infiltration that contains more than 5% of the liver’s weight. However, unlike a normal fatty liver the fatty infiltration is relatively limited and the lesions do not spread throughout the liver. Non-homogeneous fatty liver is indicated on ultrasound as an irregular flaky echo with homogeneous internal echoes, or as a strongly echogenic mass with well-defined borders and no obvious envelope, but the rest of the liver parenchyma echoes normally. Even if the patient’s fatty liver condition is improving, it is still recommended that the patient control his weight, eat a light diet, and review his liver function regularly. Therefore, if the fatty liver develops into non-uniform fatty liver, it is generally considered that the patient’s fatty liver condition has improved, but the patient should still consult the doctor in time, complete the relevant examinations under the guidance of the clinician, and take the corresponding treatment, so as to avoid delaying the condition.