“intestinal toxicity”, “intestinal wind”, “dysentery”, “locked anal hemorrhoids”, ” The disease category includes “canker sores in the anus”. For example, in the “Ling Shu? Five changes in the forty-sixth, that is, “people who are good at disease intestinal accumulation, …… skin thin but not lustrous, meat is not firm but Nao Ze, so the intestines and stomach is evil, evil is the evil stay, accumulation is injured”, the initial discussion of the intestinal “accumulation The cause of “accumulation” in the intestines is “the intestines and stomach are evil, the evil qi stays”; “Ling Shu? All the diseases begin to be born 66” listed a variety of reasons for the formation of “accumulation” in the intestines, such as “cold into the intestines and stomach …… is _flattened, _flattened is the juice and foam outside the intestines forced to gather can not be dispersed, the day to become accumulation “, “suddenly more food and drink is full of intestines, living and working inappropriately, excessive exertion is wounded, …… blood overflow in the intestines outside the cold, juice foam and blood fight, and cohesion can not be dispersed, and the accumulation into carry on”, “suddenly in the cold, …… “suddenly in the cold, if the internal injury in the anger, then the gas on the reverse, …… warm gas does not work, the blood coagulation in the not dissipated, fluid astringent seepage, and not go, and the accumulation are into carry on”, although respectively discussed the cold, diet and diet and excessive exertion, internal injury anger and other factors in the Although the role of factors such as cold, poor diet, excessive exertion, and internal injury and anger in the pathogenesis of intestinal accumulation are discussed separately, the central link is that “intestinal cold” causes “juice and blood to gather and not disperse”, so overall, “the beginning of accumulation is born with cold, and the syncope becomes accumulation. Therefore, in general, “the beginning of the accumulation is the cold, and the syncope becomes the accumulation. Ling Shu? Water distension fifty-seventh” recorded in the “intestinal Qin …… cold guest in the intestine outside, and the Wei Qi fight, gas can not be honored, because there is a system, fetish and internal, evil gas is up, meat is born”, also think “intestinal Qin, meat It is also believed that the “intestinal Qin and flesh” are caused by the invasion of cold evil, fighting with the Wei Qi, depressing the Qi, preventing the normal flow of Qi and blood, and “fetish and internal sticking”. In “Treatise on the Origin of Diseases? In the “Collection and Obstruction of the Obstruction”, it is written that “the disease is caused by cold and warmth disorder, resulting in the weakness of the Qi of the internal organs, and the diet is not eliminated, and the collection of the inner, …… growing blocks, coiled and not moving, is also the disease; …… if the accumulation leads to years and months, the person is thin, the abdomen turns big, and then leads to death. It is believed that the repeated cold and warmth disorders lead to the weakness of the internal organs, and then the diet is not eliminated and the agglomeration within, which eventually leads to the formation of “obstruction”, and points out that the prognosis is “people are thin and thin, the abdomen turns big” and death, which is similar to the death of the “abdomen”. The prognosis is very similar to that of late stage malignant tumor. Jin? Dou Hanqing’s “Complete Book of Sores and Ulcers” points out that “the dirty poison is at the end of the large intestine, which is the head of the dirty, …… poison is also vicious”, hence the name. The big one is like a plum kernel, frying cold for heat, pain is difficult to rest, the potential for swelling, turning line of false floating”. In Ming’s “Surgical Authenticity? Dirty poison” said “contains poison knot in the internal organs, fire and heat flow injected into the anus, knotted and swollen, the patient pain even small abdomen, anus fall heavy, …… helpless diet not meal, made thirsty very, where this has not seen its life”, pointed out that the prognosis is very poor. The “True Commentary on Surgery” also says that “dirty poison is born on both sides of the anus …… from internal carbuncles, and yin deficiency damp heat, down to the anus, internal knot congestion swelling, stabbing pain like a cone, constipation, urine dripping, cold and heat, especially at night, …… their sufferers The pain is even in the small abdomen, the anus is heavy …… internal erosion of the anus, often rotting the meridians, the flow of sewage, the large hole is not prohibited”, pointing out that the onset of “dirty poison” can appear similar to “carbuncle It is noted that the onset of “dirty poison” can be similar to that of “carbuncle”, with poisonous swelling, flesh rotting and pus flowing, painful and even fistulas forming, and in serious cases, as pointed out in the Qing “Medical Supplement? In serious cases, as pointed out in the Qing Dynasty’s “Anal Canker”, “redness and pain around the anus, …… and several ulcers, is known as a pan-anal canker”. Therefore, it is not difficult to understand that if the poisonous flesh is rotten, the blood is ulcerated into pus and the disease is high, abdominal pain, shortness of breath, and pus and blood are present, it is “dysentery”; if the heat poison is mild, only the ulcerated meridians and blood in the stool are the main cause, it is “intestinal wind”. In addition, if the tumor surrounds the anus and causes the narrowing of the anus, as recorded in “Surgery”, “the anus is locked inside and outside like a bamboo joint, shaped like a jellyfish, with urgency and heaviness, the stool is thin and flat, and the foul water flows sometimes, there is no cure for this, it is called locked hemorrhoid”. The prognosis is very poor. Based on the summary of ancient experience and modern medical research results, combined with his own clinical practice for many years, Dr. Sun pointed out that the etiology and pathogenesis of colorectal cancer are mostly attributed to the following conditions: 1, damp-heat injection: mostly due to uncontrolled diet, drunkenness and satiety, wanton eating of fat and sweet, or long infected intestinal diseases, long diarrhea and dysentery, or emotional disorders, liver and spleen disharmony, damage to the spleen and stomach, damp-heat internal growth, injection into the anus, knotted and swollen, pain even less abdominal, anus heavy fall, pus and blood in the stool, bowel obstruction. 2.Incompetence in drinking and sex: Indulgence in drinking and sex damages the spleen and kidneys; deficiency of the spleen and kidneys leads to accumulation; accumulation leads to deficiency; Qi is not smooth; poisonous evil accumulates in the internal organs and forces down the large intestine, resulting in swelling. 3, the external evil poison: do not avoid the cold and heat, or sit for a long time in the wetlands, wanton delay, long time no stool, so that the yin and Yang is not harmonious, the Guange congestion, wind and heat down the rush, is born five hemorrhoids. As the large intestine is one of the six internal organs, the Division of conduction, clearing the dregs, “transferring things but not hiding”, such as the above internal and external factors resulting in dampness and heat contain toxins, gathered in the internal, “hiding but not going”, anti-stagnation and swelling, is the standard evidence of colon cancer; spleen and kidney deficiency, positive qi The deficiency of spleen and kidney and the insufficiency of positive qi can not promote the conduction of large intestine, which is the root of colorectal cancer disease DD is so because “the positive qi exists inside, evil cannot dry” and “where evil comes together, its qi must be deficient”. Based on the deep explanation of the above etiology and pathogenesis, Dr. Sun pointed out that the overall treatment of colorectal cancer should be based on strengthening the spleen and kidney, supporting the righteousness to promote the conduction of the large intestine; locally, it should detoxify the dampness, disperse the knots and eliminate the stasis, and eliminate the stagnation to facilitate the recovery of the function of the large intestine. Based on many years of clinical practice, we summarize the classification as follows [2-3]: 1) for those with damp-heat nodules, the prescription is to clear heat and dampness, detoxify and fight against cancer, and the prescription is to add flavor to Sophora Diyu Tang or Paeoniae Tang; 2) for those with spleen deficiency and dampness nodules, the prescription is to strengthen the spleen, resolve dampness, detoxify and fight against cancer, and the prescription is to add flavor to Ginseng Ling Bai Zhu San or Huang Qi Jian Zhong Tang; for those with liver depression and spleen deficiency, the prescription is to add flavor to Yi Yao San; 3) for those with spleen and kidney yang deficiency and cold evil For those with deficiency of liver and kidney yin and intestinal dryness, the treatment is to nourish yin and clear heat, benefit water and conceal wood; the prescription is to add flavor to Liu Wei Di Huang Wan; 5) For those with deficiency of the right and evil and deficiency of both qi and blood, the treatment is to benefit qi and nourish blood, detoxify and fight cancer; the prescription is to add flavor to Ba Zhen Tang. In addition to the main formula of the disease mechanism, we should add and subtract according to the evidence: 1) detoxification and anti-cancer: choose beehive, vine root, red vine, septoria, caoheche, snake tongue grass, white ying, etc.; if the heat toxicity is strong, add fu ling, ground elm, acacia flower, etc.; 2) diarrhea and dysentery do not stop: add fried wu mei, pomegranate peel, horseradish, fried coix seed, etc.; if necessary, add diuretic and antidiarrheal drugs, such as pig ling, zedoary, plantain, etc.; 3) bleeding a lot: add blood surplus char, cypress char, root char, root yu char. (4) Tumor compression and flowering: add Cichorium, Huang Yao Zi, Xia Gu Cao, Sheng Oyster, Turtle Board, Turtle Nail, Pierced Mountain Nail, etc.; (5) Pain: add Yu Jin, Xuan Hu, Wu Yao, Xiang Shen, Wicker, Tao Ren, Shui Saffron Zi, Ling Xiao Hua, etc. Third, prevention before disease Modern research [4] shows that the main precancerous lesions of colorectal cancer have been identified, about 80% of colorectal cancer evolved from colorectal adenoma, and the evolution from adenoma to cancer takes about 5 to 10 years. Therefore, Dr. Sun believes that actively intercepting and reversing the disease during this 5-10 years can effectively prevent the occurrence of colorectal cancer. The strategy of “not treating existing diseases and treating future diseases” is a strategy of disease prevention and health care that was put forward as early as in the Yellow Emperor’s Classic of Internal Medicine, which includes various aspects such as preventing diseases before they occur, preventing changes after they occur and preventing dangers after they occur, which requires people to not only treat existing diseases but also prevent future diseases, pay attention to blocking the occurrence and development of diseases and adopt effective methods before they occur. This requires people not only to be able to treat existing diseases, but also to prevent future diseases, to pay attention to stopping the occurrence and development of diseases, and to use effective methods to grasp the initiative of preventing and treating diseases before they occur, so as to achieve the “art of superior work. Sun’s clinical practice over the years has led him to conclude that Cao Zhi Zi is effective in suppressing adenomas and preventing cancer. Traditional Chinese medicine believes that C. ophiopogonis belongs to the large intestine and liver meridian, and has the effects of clearing heat and detoxifying, intercepting malaria and stopping dysentery, and corroding warts, etc. It is used for dysentery, malaria, and external treatment of warts and corns, etc.; and modern medical research shows that C. ophiopogonis oil emulsion has a significant inhibitory effect on colorectal cancer cells, and it is positively dependent on drug concentration and duration of action [5], and has a certain reversal effect on multidrug resistance, and can significantly inhibit the activity of DNA topoisomerase II [6]. Therefore, it is often used by Sun Shi to prevent diseases before they occur, but it should be noted that C. ophiopogonis is toxic and its volatile oil is strongly irritating to the skin and mucous membranes, so the dosage should not be too large. Typical cases Case 1 Patient Li Moumou, female, 42 years old, from Liaoning, was first diagnosed in August 2004. At the end of 2003, the patient was diagnosed with increased stool frequency, mucus and blood in stool, accompanied by abdominal pain and shortness of breath, and was seen at a local hospital. In May 2004, the patient’s condition worsened again, with more mucus in the stool, blood in the stool, abdominal pain, urgency and heaviness, which could not be relieved by antibiotics and herbal treatment, and an egg-sized mass could be palpated in the right upper abdomen, with tenderness and hard texture. The mass was found to be about 3.4×4.5 cm, protruding into the lumen, with bleeding on the surface, and there were three nodules near the hepatic hilum, with hard texture and rough surface, the largest being 3.2×2.8 cm and the smallest being 1.5×2.0 cm. The colon mass was removed and biopsy was performed. The postoperative pathology was hypofractionated adenocarcinoma. After 2 courses of chemotherapy, he discontinued chemotherapy and came to our clinic because he could not tolerate the chemotherapy reaction. At the initial consultation, he had a dull complexion, fatigue, shortness of breath, lazy speech, pale eyelids, nausea, abdominal pain and belching, stool in the form of paste, 3-5 times/day, dull tongue, white greasy coating, and sunken pulse. Auxiliary examination: blood: WBC 3.2×109/ L, N 58%, Hb 67g/L. Stool: erythrocytes 3-5/HP, leukocytes 0-2/HP, occult blood (±). The treatment is to strengthen the spleen and resolve dampness, detoxify the toxin and fight cancer. 10g, 15g of turtle nail, 20g of Agaricus blazei, 20g of yam, 30g of chicken blood vine, 15g of substitution ochre, 30g of chicken internal medicine, 30g of raw malt, 15g of citron. 1 dose every 2 days, divided into 2 doses daily. When the stool is dry, add 30-40 grams of Atractylodes macrocephala and 10 grams of Radix et Rhizoma atractylodis Macrocephala; when the stool is loose, add 10 grams of Gold cherry seeds and 10 grams of Raspberry; when the stool is dry and then loose, add 20 grams of Evening silica and 10 grams of Fried soapberry; when the stool is urgent and then heavy, add 10 grams of Green peel, 10 grams of Child’s tea, 10 grams of Huang Lian and 10 grams of Qin Pi. After treatment for more than 4 years, the symptoms have been significantly relieved, the spirit has improved, the appetite has improved, the stool is clear, the mood is stable, the blood routine has been repeatedly rechecked within the normal range, and the liver metastases have been basically stabilized by repeated abdominal ultrasound examinations.