The clinical manifestations and diagnosis of Hashimoto’s disease have been explained in the literature before, and many patients feel worried and fearful after finding out that they have Hashimoto’s disease, but in fact, Hashimoto’s disease is not that terrible. The main aspects of treatment are as follows: 1. For those with a clear diagnosis, no goiter and hypothyroidism generally do not need treatment or only symptomatic treatment is made. Zhengzhou University First Affiliated Hospital General Surgery Department Yin Detao 2, mild enlargement of the thyroid gland is obvious, no hypothyroidism, can should be treated with thyroxine to avoid further enlargement of the thyroid gland; for those who have hypothyroidism need to use thyroxine replacement therapy, thyroxine treatment should start with a small dose, gradually increase the amount of medication, and gradually reduce the amount when it reaches the reduction criteria, therefore, the treatment of the disease requires patients Therefore, the treatment of this disease requires patients to be reviewed several times in time and the dose of medication should be adjusted in time. For those who have hyperthyroidism symptoms, symptomatic treatment is needed. Transient hyperthyroidism can be treated without anti-thyroid drugs, and only symptomatic treatment such as insulin or anti-inflammatory pain can be used, while those with heavy or long hyperthyroidism need to take anti-thyroid drugs, and patients are required to review them in time and adjust the drug dose in time. 4. For those with pain, obvious enlargement of the thyroid gland or poor results of thyroid dwelling treatment, prednisone treatment is required and the patient is asked to review it in time. 5. For patients with obvious enlargement of the thyroid gland with tracheal compression, patients with tumor nodules in the thyroid gland or patients with combined thyroid adenoma should undergo surgery in a timely manner. Therefore, patients with combined thyroid nodules should be alert and require timely surgical treatment to avoid delaying the disease. According to our years of clinical experience, Hashimoto’s disease is not the most serious disease among all thyroid diseases, but patients are required to choose a regular hospital thyroid specialist for timely examination and treatment once they find enlargement and discomfort in the thyroid area of the neck, so as not to delay the disease.