The severity of consecutive premature beats is largely based on the clinical specifics of the patient. It is closely related to the underlying disease and cannot be generalized. A premature beat in the absence of organic heart disease does not increase the patient’s risk of sudden cardiac death, which is not serious. If serial premature beats occur on top of severe organic heart disease, they are more serious and require aggressive treatment of the underlying heart disease and, if necessary, beta-blockers to improve the patient’s condition. For acute myocardial infarction, polygenic premature ventricular beats are a type of malignant premature ventricular beats, which, if left untreated aggressively, may lead to serious malignant arrhythmias such as sustained ventricular tachycardia, or even lead to ventricular fibrillation, and the patient may die suddenly. It is recommended that patients should not judge or diagnose on their own based on one result, but should consult a doctor in time, who will analyze the situation according to the specific circumstances and make a clear diagnosis.