Some patients with chronic kidney disease are diagnosed with hyperphosphatemia, and inevitably patients ask: Is this disease serious? Does it matter? This is like high blood sugar, doctors will say to patients: high blood sugar itself is not the problem, will cause a series of complications is the problem. The same is true for hyperphosphatemia. Phosphorus is a common mineral in the body like calcium, but we rarely hear the phrase “phosphorus supplementation” because most foods contain phosphorus, which makes it easier for “phosphorus” to be too high in the body, and kidney disease can aggravate high phosphorus, and high phosphorus for Kidney disease can be dangerous for patients with kidney disease. Kidney disease can lead to difficulties in phosphorus excretion due to progressive renal failure; hyperparathyroidism due to low calcium can lead to increased urinary phosphorus reabsorption and often higher blood phosphorus and lower blood calcium; and excessive vitamin D intake can lead to hyperphosphatemia. High phosphorus can cause secondary hyperparathyroidism, changes in calcium and phosphorus deposition, impaired vitamin D metabolism, and is an important factor in renal bone disease, and more importantly, can cause calcification of coronary arteries and heart valves, increasing the likelihood of cardiovascular events such as myocardial infarction in patients with kidney disease. Patients with chronic kidney disease in the long-term struggle with kidney disease, to strengthen the prevention of hyperphosphatemia and pay attention to limit the intake of high phosphorus food, when necessary, under the guidance of doctors to use some phosphorus drugs.