How long a patient can live with severe pancreatitis depends on whether the patient can survive the acute phase. The overall mortality rate of acute pancreatitis is about 15%, and if the patient develops septic shock and multiple organ failure, the mortality rate reaches more than 50%. If they survive the acute phase, some patients can live for a long time, but their quality of life may be affected to some extent. Severe pancreatitis is a life-threatening disease, and patients may have symptoms such as hypocalcemia and hyperglycemia, and endangered patients may also develop cullen’s sign and grey-turner’s sign, along with hemodynamic disorders and signs of multi-organ functional impairment. If they respond well to drug therapy, they can be clinically cured. However, in some patients, even with the application of multiple drugs or surgical intervention, the disease progresses progressively to multiple organ failure or even shock, with a very high mortality rate. Once the acute risk phase is passed, the acute life-threatening impact on life expectancy is generally reduced, but the impact on quality of life is greater due to severely impaired pancreatic function.