Varicose saphenous veins with thrombus are commonly treated with medication and surgery, and the treatment is aimed at controlling the thrombus. 1. Drug treatment: Drugs can partially relieve some of the symptoms caused by thrombosis, but cannot cure it. Commonly used anticoagulant drugs include: warfarin, low molecular heparin, etc. (Please consult a specialist to determine whether the patient is suitable for such drugs). Aspirin can also be given as an anti-inflammatory, depending on the patient’s condition, to help with the inflammation. For early thrombosis (within 48 hours of thrombosis), thrombolytic therapy with drugs such as urokinase can also be given through the interventional route. 2. Surgery: minimally invasive surgery or traditional surgery. Doctors can perform surgery such as high saphenous vein ligation and vein stripping to remove the thrombus caused by varicose saphenous vein. After the surgery, the patient should continue to wear compression stockings and local compression as prescribed by the doctor to minimize postoperative leakage. Patients diagnosed with saphenous varicose vein with thrombus should actively cooperate with the specialist’s treatment plan, and should not use medication on their own, so as to avoid delay in treatment or discomfort.