The liver is a sensitive organ, easily damaged by various factors such as viruses, drugs, alcohol, immune factors and so on can cause liver damage, but liver damage does not easily produce symptoms, especially chronic liver damage, so the liver is also a silent organ. As the old saying goes, “A sickness comes like a mountain, and a sickness goes like a silk”, which could not be more aptly applied to patients with cirrhosis. The common causes of cirrhosis are hepatitis viruses, most commonly hepatitis B virus, hepatitis C virus and hepatitis D virus infections. There are also alcoholic factors, cholestasis, bruising factors, pharmacological or chemical toxic factors, metabolic disorders, parasitic infections and other factors. In China, alcoholic cirrhosis accounts for about 10% of the total number of hospitalized cirrhosis in the same period. Malnutrition can reduce the resistance of hepatocytes to toxic and infectious factors, and become an indirect cause of cirrhosis. Some of the causes of cirrhosis are unknown and are called cryptogenic cirrhosis. Once a patient finds out he has cirrhosis, he desperately hopes that his doctor can give a “magic pill” to cure him as soon as possible, and never relapse. The patient is unaware that cirrhosis is a “disease that goes away like a tug of war”. Cirrhosis is a gradual formation of liver pathological changes on the basis of various chronic liver diseases, generally speaking, the occurrence of cirrhosis takes at least 5-10 years. This process, due to various etiological factors such as viruses and alcohol, leads to inflammation and necrosis of liver cells, stimulates the proliferation of liver fibrous tissue, and more and more liver fibrous tissue is deposited in the liver, exceeding the metabolic capacity of the liver, thus causing disorders in the structure of liver lobules and the formation of pseudobullets, i.e., entering the cirrhosis stage. There is no distinct line between liver fibrosis and cirrhosis, it is a continuous process. That is to say, the formation of cirrhosis undergoes a long process. So, can cirrhosis be reversed? In recent years, there is increasing evidence that cirrhosis can be reversed to some extent with long-term control of the cause of the disease. In particular, satisfactory results have been achieved in the treatment of hepatitis B cirrhosis in some patients. In the treatment of cirrhosis, treatment of the cause of the disease is fundamental. Take “hepatitis B cirrhosis” as an example. The long-term existence of hepatitis B virus, i.e., active replication, is the cause of the disease, so antiviral treatment is fundamental and a prerequisite. However, the control of the cause is not the same as the direct improvement of cirrhosis. The gradual repair of liver fiber tissue accumulated over decades requires a long process, which is why the treatment of cirrhosis is “as slow as a wire”.