After on the hemorrhoid cream more pain is generally due to the patient exists anal fissure or external hemorrhoid rupture by the drug stimulation more pain. If the patient himself has anal fissure or ruptured hemorrhoids, after the hemorrhoid cream, the wound is stimulated by the drug, there will be pain, it is recommended that the patient first stop using hemorrhoid cream, you can use diclofenac sodium internal anus or intramuscular injection of clonoxicam, which can play a role in anti-inflammatory, pain-relieving effect. Patients can use the drug for 3-4 days after the symptoms have improved, wound healing and then use hemorrhoid cream, usually pay attention to the perianal area of dryness, hygiene, to avoid constipation, diarrhea, feces too hard, so as not to aggravate the condition. If the situation of hemorrhoids is serious, it is recommended to go to the hospital, under the advice of the doctor for further treatment.