The following reasons are considered for chest tightness and lack of appetite: 1. anemia: when anemia occurs, there will be weakness, chest tightness, shortness of breath, loss of appetite, dizziness and other uncomfortable symptoms. 2. chronic diseases: such as liver failure, renal failure, will be secondary to hypoproteinemia, complicated by pleural effusion, the patient will also have symptoms such as chest tightness, the condition will be accompanied by loss of appetite, weakness, etc. 3. acute heart failure: the patient will have chest tightness and other uncomfortable symptoms, because the body circulation stasis will lead to gastrointestinal stasis, digestive function will be significantly reduced. 4. 4, chronic gastric disease: such as gastric cancer, gastroesophageal reflux disease, esophageal cancer, etc., acid reflux appears as chest tightness, shortness of breath and other symptoms, often accompanied by bloating, belching, decreased appetite and other digestive system symptoms. When the above symptoms appear, it is necessary to seek medical attention immediately and give comprehensive examination and treatment under the guidance of doctors to avoid delaying the disease.