The maintenance of normal reproductive function requires a certain amount of fat storage and an adequate nutritional environment, but the effect of body weight on reproductive function becomes a bipolar distribution. We know from ancient books that “Danxi treatment method of the heart? Volume 7: “fat infertility, because the body fat occlusion of the uterus, menstruation does not work, with the guide phlegm and so on; thin infertility, because the uterus without blood, essence does not gather, with four things to nourish the blood, nourishing Yin and other drugs. Qing? The woman’s family is a very important part of the family. Those who have a thin woman who cannot become a fetus, or those who have internal heat and much fire, the blood in the uterus is withered, unable to congeal sperm, the ulnar pulse is flooded and floating, when nourishing Yin and lowering fire, smooth Qi and nourishing Blood is the mainstay.” Normal reproductive function is regulated by the hypothalamic-pituitary-ovarian axis (headquarters) which, through a series of adjustments (tugging at the skin), releases hormones (instructions) to promote follicle development and maturation and expulsion (expatriate), and the union of the egg with the sperm (the other messenger) and implantation in the endometrium (the designated area) and pregnancy (the final crystallization). Closely related to weight, ovarian tissue has an enzyme system that directly takes in cholesterol to synthesize sex hormones (and fat closely related to the contact sector), and pregnenolone synthesized from cholesterol is the precursor substance for synthesizing all sex hormones, so a certain fat content is a prerequisite for the development of female reproductive function (without the operation of fat, there is no way to complete the contact, and without the contact neither can rip to the headquarters, nor can the headquarters send out the eggs) The body needs a critical or appropriate amount of fat to initiate pubertal development, maintain ovulation and undertake pregnancy (that is to say, the amount of fat is too much especially). The central nervous system is very sensitive to weight loss, and persistent wasting can cause GnRH to drop to prepubertal levels, making gonadotropin and estrogen levels low and preventing ovulation, as well as genital atrophy in long-term amenorrhea, leading to infertility. Excess weight and obesity are pathological states in which the number of fat cells in the body increases or the volume increases, and fat (mainly triglyceride) accumulates excessively, making the body weight more than 20% of the standard weight. Although a certain amount of fat is a prerequisite for the development of female reproductive function. However, in humans, there is a “GnRH pulse generator” in the medial base of the hypothalamus that secretes GnRH in intermittent pulses, with a secretion cycle of about 60-100/min in adults and about 60/min in fetuses. When the GnRH pulse generator is slowed down for some reasons, the drive of GnRH to the pituitary gland in the body is weakened and the secretion of FSH and LH by the pituitary gland is correspondingly reduced, resulting in a secondary reduction of FSH and LH input to the ovaries and different degrees of ovarian damage. Clinical manifestations often include ovulation disorders, menstrual disorders, amenorrhea, spontaneous abortion, and infertility (a simple understanding is that normal pulses correspond to normal weight ranges, and when weight increases, the number of pulses decreases relatively). Leptin is a biologically active peptide hormone secreted by adipose tissue, which is associated with hypothalamus． Pituitary gland. The maintenance of gonadal axis function and follicular development are closely related. （I have seen yellow, oily fat particles around the fallopian tubes, which are like a plaster-fixed arm and have a significantly reduced ability to grab small eggs from around the ovaries. Although the above mentioned factors make it difficult for many fat people to get pregnant, there are not a few who get pregnant at 180 pounds. Normal women have an active glucose metabolism during pregnancy, there are target cells against insulin action, the placenta produces insulin enzymes that destroy insulin resulting in increased insulin needs during pregnancy, so pregnancy has a metabolic triad of hyperglycemia, insulinemia and relative insulin resistance associated with the formation of excess weight, this relationship is more prominent in obese overweight women, prone to gestational diabetes, while obese women have abnormal lipid metabolism during pregnancy. The risk of pre-eclampsia (hypertensive disorders of pregnancy) is greater, and the rate of giant fetuses and cesarean deliveries is significantly higher than others.