Mycoplasma bronchiseptica is a clinical disease in which coughing and coughing occur due to congestion and edema of the bronchial mucosa caused by infection with mycoplasma. Mycoplasma is a pathogenic microorganism smaller than bacteria. Respiratory infections are commonly caused by bacteria, viruses, and then atypical pathogenic bacteria, including mycoplasma, chlamydia, and legionella. Mycoplasma is generally common in children’s infections and the elderly and other weaker people are prone to mycoplasma infection, mycoplasma treatment has a special medication, generally with cephalosporin, penicillin effect is not good, more special treatment drugs are macrolides, like roxithromycin, azithromycin are more sensitive. If a child has a long-term cough, coughing phlegm, bronchitis performance for a long time, with the general anti-inflammatory drugs or antiviral drugs is not effective, then we must exclude mycoplasma infection, if mycoplasma infection positive, we must take the corresponding macrolide treatment, symptomatic treatment effect will be obvious.