IVF can be considered in the following cases: 1. The female partner has difficulty in meeting the sperm and egg due to tubal factors (1) Bilateral tubal resection or bilateral tubal incompetence. (2) One side of the fallopian tube is removed, or one side of the fallopian tube is incompetent, while the other side of the fallopian tube is open but extremely incompetent, or combined with pelvic adhesions. (3) One side of the fallopian tube is removed, or one side of the fallopian tube is incompetent, and the other side of the fallopian tube is patent, and artificial insemination fails to produce pregnancy. (4) Bilateral incompetent fallopian tubes combined with pelvic adhesions; or no pregnancy for more than 6 months after laparoscopic surgery or no pregnancy by artificial insemination after surgery. (5) Severe hydrocele in the fallopian tubes. (6) Severe pelvic adhesions. (2) Ovulation disorder (1) persistent anovulation without pregnancy after repeated ovulation treatment; (2) evidence of significant ovarian hypofunction; (3) endometriosis In mild cases, intrauterine insemination can be attempted; in severe cases, those ≥35 years old or those with hypofunction of ovaries and those with recurrence of endometriosis after surgery, IVF can be performed directly to assist pregnancy. 4.Low and weak spermatozoa in the male partner 5.Unexplained infertility For patients with unexplained infertility and ≥3 cycles of failed intrauterine insemination, IVF is recommended to assist pregnancy.