The most direct way to confirm the diagnosis of novel coronavirus pneumonia is to detect the nucleic acid of the novel coronavirus, either by collecting a nasal swab, a pharyngeal swab or isolating the virus from the patient. Because novel coronavirus pneumonia can be clinically classified into mild, common, symptomatic, and critical cases, there are also asymptomatic infections. Asymptomatic infections can have no clinical symptoms and can only be diagnosed by a positive nucleic acid test. Because novel coronavirus pneumonia is an infectious disease, even if the nucleic acid is negative, if the patient has epidemiological data, i.e., has had contact with patients with confirmed novel coronavirus, or has a history of travel or residence where community cases have been reported, has typical clinical symptoms of novel coronavirus pneumonia such as malaise, dry cough, fever, or is accompanied by diarrhea, nasal congestion, runny nose, sore throat, etc. Blood tests suggesting low white blood cells or lymphocytopenia and lung CT with typical manifestations of viral pneumonia, such as the presence of ground glass shadow and interstitial changes, can be diagnosed as a suspected case. Patients need to be isolated in a single room, multiple nucleic acid collections and serological tests, and the diagnosis can be confirmed if IgM is positive or IgG is increased fourfold or more in two sera.