Tightness and pain in the back and front of the chest at night may be due to reflux esophagitis, angina pectoris, heart attack, muscle strain, herniated disc, neuropsychiatric disorders, etc., and are usually treated with medication or surgery. The use of medication should be in accordance with medical advice. 1. Reflux esophagitis: it can be caused by stomach acid burning, resulting in pain in the chest and back, as well as chest tightness and discomfort, etc., and need to follow the doctor’s advice to use acid-suppressing gastric protection, to promote digestion of drugs, such as omeprazole, cimetidine, domperidone. 2. Angina pectoris: is due to myocardial ischemia and hypoxia caused by transient cardiac pain, accompanied by chest tightness, chest pain or pain radiating to the back, generally comply with the doctor’s instructions to use nitroglycerin to expand the crown can be relieved. 3. Heart attack: chest pain and back pain, can be radiated to the left upper limb, the need for anticoagulation and thrombolytic therapy, need to follow the medical advice to take aspirin, clopidogrel and other drugs, if necessary, interventional surgery. 4. Muscle strain: If the exercise to the pectoral muscles, lumbar and back muscles and other parts of the body, can cause muscle strain caused by boring pain, can be appropriate massage and physical therapy, the pain is more serious can be prescribed to take ibuprofen, diclofenac sodium, and other drugs to relieve pain. 5. Intervertebral disc disease: when there is a thoracic disc degeneration and herniation, it can also cause chest and back pain, you can consult the doctor to use ibuprofen and other drugs to relieve pain, or take surgical treatment. 6. Neuropsychiatric diseases: Neurosis can cause chest and back pain, need to do electrocardiogram, cardiac ultrasound and other tests to check whether there are organic lesions, can be under the guidance of the doctor for psychotherapy, drug therapy, such as ghrelin, zopiclone and so on. It is recommended that patients go to the cardiovascular department or gastroenterology department in a timely manner, and follow the doctor’s instructions to standardize the use of medication, to avoid blind use of drugs and delay the condition.