Cirrhosis is a descriptive diagnosis that describes a liver that has hardened and become yellowish-brown in color. Cirrhosis is caused by multiple causes and is a chronic, progressive, diffuse inflammatory as well as fibrotic liver disease. Under the repeated or continuous action of some pathogenic factors, hepatocytes in the liver show diffuse degeneration, necrosis, and apoptosis, and the remaining hepatocytes regenerate to form regenerative nodules, diffuse proliferation of connective tissue, fibrous tissue separation, and eventually fibrous tissue division or destruction of normal liver lobular structure to form pseudolobules, called sclerotic nodules, or pseudolobules such a characteristic pathological change. The clinical manifestation is impairment of liver function with or without symptoms of portal hypertension. There are many causes of cirrhosis, including cirrhosis caused by chronic hepatitis B, hepatitis C, alcoholic liver, non-alcoholic fatty liver disease, drug-related liver disease, autoimmune liver disease, cholestasis, and some rare causes such as Buga’s sign and hepatomegaly.