Epalrestat tablets are mainly used for the treatment of diabetic peripheral neuropathy, diabetic peripheral neuropathy taking Epalrestat has no effect, usually associated with improper medication, improper diet, the severity of the disease and other factors, can be combined with the cause of the general treatment and medication to control the progress of the disease. 1. Improper medication: taking Epalrestat may affect the therapeutic effect if it is not strictly in accordance with the requirements, or stopping or reducing the dosage without authorization. The treatment should be reasonable, avoid unauthorized discontinuation, if the effect is not good, you can switch to other drugs, such as vitamin B12. 2. Improper diet: During the period of taking Epalrestat, if the diet is unreasonable, long-term intake of high sugar, high fat, high calorie food, easy to lead to the rise of blood glucose, thus affecting the control of diabetic peripheral neuropathy. When dealing with it, some improvements should also be made in terms of diet, trying to be light, easy to digest, low-fat, low-calorie and low-sugar as the principle. 3. Serious condition: When peripheral neuropathy is more serious, taking Epalrestat alone is not effective and should be combined with drugs that can improve nerve blood supply. Note that Epalrestat is contraindicated in case of allergic reactions. This drug may cause thrombocytopenia, liver function impairment, erythema, blisters, rash, itching and other adverse reactions. Regular observation is recommended during the use of the drug, and the specific use of the drug should be carried out in strict accordance with the doctor’s instructions.