Urticaria after drug allergy generally refers to chronic spontaneous urticaria, which is treated by discontinuing the suspected drug, topical application of the drug, oral medication and other methods. 1. Stop using drugs: chronic spontaneous urticaria itself belongs to a recurrent disease, this disease can even be up to several months or years, part and some of their own systemic diseases or infections, and the use of drugs will aggravate the condition. The first thing to do is to stop using suspicious drugs, such as aspirin, non-steroidal anti-inflammatory drugs, penicillin, angiotensin-converting enzyme inhibitors, anesthetics, ethanol and so on. 2. Topical application of drugs: hives usually appear more serious itching, you can apply topical glycerine lotion, hydrocortisone cream, etc. to relieve itching. 3. Oral medication: you can take cetirizine, loratadine, vitamin C and other drugs to improve the allergy, if necessary, can be combined with chlorpheniramine, cyproheptadine, ranitidine and other drugs together. For the above treatment is ineffective or more difficult to cure, often repeated episodes, you can use omalizumab, cyclosporine and other drugs. Drug allergy hives can not be cured should be timely consultation, under the guidance of the doctor standardized treatment, the above drugs should be used in accordance with medical advice.