Pregnancy toothache fast pain relief using localized irrigation or open pulp treatment. Pregnant women’s toothache is common in endodontitis, apical periodontitis, wisdom tooth pericoronitis, because pregnant women are special people, applicable drugs are less, pain relief generally take local rinsing or open pulp treatment. 1. Pulpitis: when pregnant women have pulpitis, there will be paroxysmal pain, night pain, hot and cold pain, can follow the doctor’s advice to use root canal treatment to open the pulp treatment can be effective pain relief. For acute suppurative pulpitis appear hot pain cold relief, you can gargle cold water temporary pain relief, followed by root canal treatment. 2. Apical periodontitis: apical periodontitis will have teeth biting pain, knocking pain, inflammation develops to the periodontal tissues, at this time should be used in accordance with medical advice to open the pulp to relieve the pressure of the pulp cavity, and if there is an abscess formation, it must be incised and drained to discharge the pus, and the pain can be relieved. 3. Wisdom tooth pericoronitis: when the wisdom tooth eruption is blocked, local inflammation will be produced, through the local rinsing of the blind pocket, the oozing liquid and food residues rinsed out, the inflammation will gradually subside, and the pain can be relieved. If a pregnant woman has a toothache, it is recommended that she consult a doctor in a timely manner to clarify the cause of the disease, and then take appropriate intervention according to the doctor’s recommendations to avoid self-medication, which may result in adverse consequences.