Diabetes with high blood pressure when taking valsartan or irbesartan need to be under the guidance of a professional doctor, choose the antihypertensive drugs suitable for their own conditions, not to decide on their own. Valsartan or Irbesartan is an angiotensin II receptor antagonist, this product does not affect the hypoglycemic drugs to lower blood sugar, and there is a certain protection of renal function. It is suitable for patients with diabetes mellitus accompanied by hypertension. The common adverse effects of angiotensin II receptor antagonists are headache, edema, and increased blood potassium. Allergy to the components of the product is prohibited, pregnant and breastfeeding women are prohibited. When using the drug should be careful with potassium-preserving diuretics, such as spironolactone should be monitored blood potassium, to avoid causing hyperkalemia; severe renal insufficiency patients should be prohibited; hepatic insufficiency patients should be adjusted dose. Valsartan or Irbesartan is a commonly used antihypertensive drug in clinical practice, and should be used under the guidance of a doctor.