Graves’ disease (toxic diffuse goiter) and Graves’ disease hyperthyroidism can be treated with iodine-131 in the following cases: 1, abnormal liver function, leukopenia is not suitable for antithyroid drug (ATD) treatment; allergic to the ATD drug; 2, recurrence after ATD treatment; 3, recurrence after surgery or unwilling to surgery; 4, toxic nodular goiter with hyperthyroidism (Plummer disease); 5, chronic lymphocytic thyroiditis with Graves’ disease; 6, non-toxic goiter from the cosmetic point of view can also be used for iodine-131 treatment. Plummer’s disease; 5, chronic lymphocytic thyroiditis with Graves’ disease; 6, non-toxic goiter from the cosmetic point of view can also be used iodine-131 treatment.