Everyone knows the greatness of motherhood and that “you don’t know the kindness of your parents until you raise your children”. The reward for the mother is the care and filial piety of the mother in her old age. This reward requires a long wait and a lot of hard work. However, recent scientific research has shown that the fetus has already rewarded the mother by giving her some mysterious gifts: some fetal cells magically penetrate the placental barrier into the mother’s body and stay there for a long time, playing a wonderful role in repairing maternal damage and suppressing tumors. The scientific community has confirmed that the child’s cells remain in the mother’s blood and organ tissues, and they have been found in the mother’s spleen, liver, lungs, kidneys, brain, bone marrow, thyroid and skin. The cells that “migrate” from the fetus to the mother are not mature cells, but are similar to stem cells. In layman’s terms, it is like a “baby cell” that has not yet decided what it will eventually become when it enters the mother’s body, and therefore has the ability to form any type of cell in the mother’s body. This cell is called the “gestation-associated founder cell” or “fetal microchimer” in the mother’s body, and it maintains the ability to differentiate and replicate in the mother’s body, an ability that is undoubtedly a great asset to the medical community, as it can become either heart cells, but also into liver, blood, muscle or brain cells that can repair damage and lesions. The types of these fetal cells currently found in the mother are: hematopoietic stem cells (expressing CD34, CD45), epithelial primordial cells (expressing CD31), placenta-derived stem cells, cytotrophoblasts, and mesenchymal stem cells. Scientists have verified the positive effects of fetal cells on the following diseases of the mother: i. Breast cancer Previously, we knew from epidemiological statistics that women who had given birth were significantly less likely to develop breast cancer than women who had not given birth, and at that time it was presumed to be related to breastfeeding. According to a recent study published in the journal Cancer Research, researchers at the University of Washington and Fred Hutchison Research Center investigated 82 women who had given birth to boys, 35 of whom were diagnosed with breast cancer. The researchers compared male fetal deoxyribonucleic acid (DNA) sampling in maternal blood and found that 14 percent of the subjects with breast cancer had male fetal DNA in their maternal blood, compared to 43 percent of women without breast cancer. Because male fetuses contain XY chromosomes, their DNA is easier to separate than that of female fetuses with XX chromosomes, so only women who conceived and gave birth to male fetuses were used in this study. Study leader V.K. Gaddy said, “My hypothesis is that the fetal cells may recognize the embryonic breast cancer cells in the mother and kill the cancer cells before they start to be active.” Second, rheumatoid Our Chinese folklore spreads the saying that having a child to nourish the disease, through pregnancy can reduce joint pain is there for all to see. 15 years ago, Nobel laureate and American scientist Hench found that: when the baby’s HLAII is very different from the mother’s cells, pregnant women rheumatoid disease will be reduced. The higher the fetal microchimerism, the better the sense of symptom reduction of pregnant women with rheumatoid diseases. Cerebrovascular and neurological diseases Through experiments on mice, scientists have found that “pregnancy-associated primordial cells” from mice at the time of conception are able to cross the placental barrier, enter the bloodstream, and eventually reach the maternal brain, where they break through an almost impermeable biological wall After breaking through an almost impermeable biological wall – the blood-brain barrier – they carry information to the brain, where they complete their cellular repair mission. While we all know that adult nerve cells cannot regenerate once they are damaged, these fetal cells can differentiate into nerve cells in the maternal brain and proliferate, repairing damage that cannot be repaired by adults themselves. If this discovery is confirmed and validated in all people, it will be strategic for the treatment of various embolism or some neurological decline diseases such as Alzheimer’s and Parkinson’s disease one day. Fourth, skin damage Scientists found a large number of fetal cells – epithelial primordial cells at the skin injury of mice, and found that fetal cells are closely related to the repair of maternal skin damage, especially the new blood vessels. V. Chemical injury to the liver Scientists published in the journal Human Reproduction last year reported that a large accumulation of fetal cells in the liver was found in a pregnant mouse model of chemical liver injury, and the number was significantly higher at 8 weeks of gestation than at 4 weeks of gestation, and persisted in the liver after delivery, and fetal cell storage and migration in the spleen was also found. A 2004 article in the American Journal of Laboratory Observations reported that liver puncture biopsies from 14 patients with cirrhosis, 8 patients with hepatitis C, and 6 patients with other liver diseases who had given birth to a boy revealed a fetal cell detection rate of 43%, 25%, and 33%, respectively. This indicates that fetal cells can migrate in vivo to the damaged part of the mother’s body. In 2006, an article in the American Journal of Obstetrics and Gynecology reported that fetal cells were found in tissue sections of six mothers who had part of their lungs removed for lung cancer, forming a protective wall around the diseased tissue to limit the expansion of tumor cells, and it was hypothesized that these cells normally lurked in the maternal bone marrow and other tissues. Now scientists have detected fetal cells in the blood of pregnant women as early as 33 days of gestation, and this technique has been applied to prenatal diagnosis. Experiments in mice have shown that fetal cells can be detected in maternal blood at 10-12 days of gestation, appearing in organs at day 13, increasing significantly at day 16 and gradually fading after delivery, with no fetal cells detected in peripheral blood 3 weeks after delivery. In contrast, 40% of mothers retain fetal cells in the blood for a long time after the third delivery. More interestingly, 2.4 times more fetal cells were detected in mothers after spontaneous and induced abortions than in normal mothers. A life is shed, but he leaves a trace of his life by leaving his cells inside the mother’s body. And how long will this trace remain? I think: our former children will stay with us for the rest of our lives – because scientists have detected the cells of a mother’s 51-year-old son in the bone marrow of her rib cage. Of course, the “fetal microchimer” is a double-edged sword, causing autoimmune diseases in a few cases, but in most mothers it plays a long and faithful role in protecting the mother and repairing organ damage. How these fetal cells escape the maternal immune system and remain in the mother’s body for so long remains an open question. We also know that pregnancy alleviates or even cures some diseases such as lupus erythematosus, scleroderma psoriasis, skin diseases, multiple sclerosis, dysmenorrhea, gastroptosis, endometriosis, migraine, etc. Whether these miraculous phenomena are related to the mysterious gift of the fetus to the mother – fetal microchimerism remains to be further studied and confirmed by science. But in any case, we have to exclaim that creation is so amazing that it makes the bond of love between mother and son so tight that it is really “you have me and I have you.” Spiritually and physically, children are a precious gift from life to mothers!