Most patients with cerebral thrombosis develop late at night or in the early morning, when they are quiet or sleeping. Many patients with cerebral thrombosis suddenly appear to be unable to raise one arm with numbness or suddenly have slurred speech when they are resting or after waking up, which should be alerted to the occurrence of cerebral thrombosis. Since the onset of cerebral thrombosis is often late at night or early in the morning, many patients are sent to the hospital and miss the 4.5-hour time window for thrombolysis. Therefore, for people with high risk of cerebral thrombosis, such as men aged >55 years, long-term smokers, obese, with hypertension, diabetes, sleep apnea syndrome, and family history of cerebral thrombosis. Common symptoms of cerebral thrombosis, including sudden onset of dizziness, nausea, vomiting, limb weakness, numbness of hands and feet, slurred speech, facial paralysis, and swallowing disorder, should be recognized promptly. Once these symptoms appear, the patient should be rushed to the hospital for medical attention in an effort to enable effective revascularization treatment.