Patient: no obvious symptoms, in Beijing Union Hospital laboratory tests, thyroglobulin high more than 10 times, low thyroid hormone, want to know the meaning of the device has not been treated, only to find I want to know if it is early cancer? Jia Hongli: Ultrasound is the most sensitive way to diagnose malignant thyroid disease, if ultrasound describes hypoechoic nodules with sandy calcification, unclear borders,? rich blood flow, etc. means malignancy is possible and surgery should be done as soon as possible. Eventually the diagnosis is confirmed by postoperative pathology. If the TSH alone is low, it is subclinical hyperthyroidism and there is little point in doing TG before surgery. For now, you should get an ultrasound diagnosis first and then you can also go to nuclear medicine for MIBI imaging of the thyroid.