Itchy anal opening should be based on the cause of itching medication, eczema can be used loratadine tablets, etc., dry skin can be used urea ointment, etc., anal fissure can be used potassium permanganate solution, etc., hemorrhoids can be used dioxymethamphetamine tablets, etc., perianal abscess can be used amoxicillin, etc., anal fistula can be used cefuroxime and so on. 1. Eczema: Eczema patients can use glycerine lotion, zinc oxide oil, tacrolimus cream and other medications, with oral dicloxacillin tablets, loratadine tablets and other drugs. 2. Dry skin: If the skin is dry, you need to pay attention to local moisturizing, you can apply moisturizing cream, you can also apply urea ointment, viamin ester Vitamin E cream and other drugs to relieve. 3. Anal fissure: if the patient has anal fissure, you can use potassium permanganate solution diluted in a sitz bath to relieve. 4. Hemorrhoids: patients can take oral diosmin tablets and other treatments, with warm water sitz bath, and then use the compound keratine acid ester cream coated with the affected area. 5. Perianal abscess: before the formation of perianal abscess, can use erythromycin ointment and other medications, after incision and drainage, with amoxicillin, cefuroxime and other antibiotics to control the infection. 6. Anal fistula: patients with anal fistula need to use antibiotics such as cefuroxime and penicillin V potassium tablets if they have an acute attack or infection. It is recommended that patients with itchy anus should consult a doctor in a timely manner to clarify the cause of the disease, and strictly comply with the doctor’s instructions for medication, drug treatment is not effective, should also be treated by other methods.