In recent years, the number of elderly people with abnormal liver function is increasing. The main reason for this is drug-related hepatitis. As people get older, the function of each organ is gradually decaying. With the increasing number of medical examinations, advanced medical devices can be used to judge each organ, so many elderly people are examined to varying degrees for some organ damage. For example, coronary heart disease, hypertension, hyperlipidemia, diabetes, degenerative joint disease, cerebral infarction, cerebral thrombosis and so on. Some elderly people can be counted as suffering from more than 10 diseases. Theoretically, damage to the organs should of course be treated with drugs to improve and restore their function. Along with the expansion of the scope of Medicare treatment drugs, for the elderly, on the one hand, there are indeed a variety of diseases, on the other hand, in recent years, due to the improvement of the standard of living, diet structure and lifestyle has changed greatly, as well as people’s increasing awareness of medical examination, the widespread use of ultrasound, the population fatty liver detection rate is increasing. Some people with fatty liver do not take it seriously and think that it does not matter whether they see a doctor or not; others, on the contrary, are terrified once they are diagnosed with fatty liver by a doctor and seek medical advice everywhere. Since fatty liver is a rather large medical market, a large number of drugs for fatty liver are advertised to expand their influence and use the most eye-catching rhetoric to win the trust of fatty liver patients. According to rough statistics, about fifty percent or so of patients with fatty liver disease are over-treated. In fact, this rich disease is not terrible and is mostly related to poor diet. Long-term excessive consumption of high-fat food leads to elevated blood lipids and induces obesity; no panacea for fatty liver has been found at home and abroad, and the treatment mainly relies on “keep your mouth shut and your legs open”, i.e., long-term strengthening of exercise and correction of poor diet and lifestyle habits. If the fatty liver is accompanied by only mild hyperlipidemia, it is not necessary to use lipid-lowering drugs. If you have fatty liver and significant hyperlipidemia, you need to decide whether to use lipid-lowering drugs at the discretion of your doctor according to the cause and degree of hyperlipidemia. Do not use lipid-lowering drugs without authorization, as this may also cause drug-related hepatitis. For patients with fatty liver with elevated transaminases, it is also not recommended to take large amounts of long-term enzyme-lowering drugs. In fact, the increase of transaminases is mainly related to obesity. Studies have shown that for every 1% reduction in body weight, transaminase decreases by 8%; the enlarged liver shrinks and fatty liver reverses; and transaminase tends to remain elevated in those with high body weight, even if liver-protective and enzyme-lowering drugs are applied, it is difficult to be effective. At present, fatty liver is a “rich disease” after the solution of food and clothing, the national people lack not nutrition but exercise; what is urgently needed is not tonic drugs, but a scientific lifestyle. As long as the prevention principle of “eat less, move more, drink less and use drugs carefully” is achieved, the increasing prevalence of fatty liver can be effectively controlled. Most medications are reimbursable and the idea of “not eating for nothing” is at work, but it should be emphasized that all medications need to be metabolized and excreted in the liver and kidneys. A large number of drugs entering the body at the same time will inevitably increase the burden on the liver and kidneys, leading to the deterioration of the already declining liver and kidney function, and ultimately, contrary to expectations, causing irreversible damage to the body. This kind of abnormal liver function in the elderly caused by taking multiple drugs can be called “senile drug hepatitis”. So, how should I choose the medication? First, you should ask an experienced doctor to help you determine how many diseases you have. It is common sense to distinguish between “mild, severe, slow and urgent”, and to use medication in case of severe and urgent illnesses. However, for some degenerative diseases of the elderly, mainly due to the gradual decline of organ function with age, the test results are certainly not consistent with the normal value, but as long as it does not significantly affect the quality of life, and the drug can not cure the disease of the elderly, you can consider temporarily not to take drugs, using other physical therapy methods to relieve symptoms. Secondly, for chronic diseases that require long-term medication, such as hypertension and coronary heart disease, it is best to choose drugs that are simple to use and in small doses, only once a day, only one capsule of slow-release, long-acting preparations. Third, choose a good time to take the medication, the general drug is best to choose to take before or 30 minutes after a meal. Gastric drugs, including gastric mucosa protectants, are best taken before meals, while diuretics are best avoided before bedtime, the increase in urination at night will affect sleep; antihypertensive drugs are appropriate to take in the morning. It is best not to take both western and Chinese medicines at the same time, and taking them separately can reduce the adverse reactions generated by each other. Fourth, avoid taking the wrong medication because of the number of drugs. Find several small pill boxes of different shapes and colors, and store the drugs you need to take every day in separate boxes, one small box at a time, and take them regularly. Avoid taking the wrong medicine. Fifthly, for the so-called health supplements for the elderly, such as royal jelly, cerebral platinum, calcium, multivitamins, lecithin, deep-sea fish oil, etc., it is better not to take them at the same time as regular medications, because these health supplements are non-essential medications and do not need to be taken strictly on time. Finally, it is also important to remind the elderly not to store too many medications for a long period of time, as storage conditions at home are limited to avoid taking spoiled medications. Medications at home also need to be checked regularly for shelf life and should not be taken if they have exceeded their shelf life.