Raynaud’s syndrome treatment preferred can weaken the sympathetic nerve muscle contact conduction class of drugs, such as guanethidine, also can be brachial artery injection of rifampicin. 1. Guanethidine: belongs to the sympathetic nerve inhibitory drugs, can be used for the treatment of hypertension. Adverse reactions include swelling of the lower extremities, angina, diarrhea, dizziness, fainting, blurred vision, tremor, etc. It is used with caution in patients with a history of asthma and those with incomplete cerebrovascular blood supply. Guanethidine can be used in combination with phenobenzylamine in the treatment of Raynaud’s syndrome. 2. Risperdal injection: also belongs to the sympathetic nerve inhibitory drugs, applicable to patients with hypertensive crisis, common adverse reactions include lethargy, fatigue, depression, anxiety, dreamy, insomnia and so on. Cardiovascular or central reactions, such as impotence, bradycardia, and inattention, occur after discontinuation of the drug. Contraindicated in patients with depression. If the diagnosis of Raynaud’s syndrome is confirmed, it is recommended to go to the hospital in a timely manner, and standardize the treatment under the guidance of the doctor, and the drug should be used in accordance with the doctor’s instructions, do not self-medicate.