Lung alveoli are also known as pulmonary blisters, and chest pain caused by pulmonary blisters is mainly relieved by non-surgical and surgical treatments. Pulmonary alveolus is often combined with bacterial infection and recurrent pneumothorax, which in turn cause the symptoms of chest pain, and the treatment includes non-surgical treatment and surgical treatment. When pulmonary herpes is combined with bacterial infection, antibiotics such as cefoperazone should be applied for anti-infective treatment; when rupture of pulmonary alveolus leads to pneumothorax and thus causes chest pain, closed chest drainage is needed to alleviate chest pain. For patients with surgical indications, surgical treatment should be as surgical as possible, and surgical treatment mainly includes television thoracoscopic surgery (VATS), open thoracic surgery, transbronchoscopic flap blockage or bronchial blockage combined with closed drainage and other methods. When pulmonary herpes cause chest pain, they should go to regular hospitals in time and be treated under the guidance of doctors.