There is no data to suggest that administration of the Neoconazole vaccine on the first day of menstruation will affect the immune effect of the vaccine or aggravate adverse reactions after vaccination. The contraindications to vaccination in the Technical Guidelines for Vaccination against Neocoronavirus (First Edition) issued by the Health and Welfare Commission also do not mention that vaccination is not allowed or needs to be postponed during menstruation or on the first day of menstruation. In contrast, the Guidelines on Contraindications and Precautions for Neocoronavirus Vaccination clearly state that Neocoronavirus vaccination can be administered during menstruation. Therefore, if there is no discomfort such as fever or abdominal pain on the first day of menstruation, you can receive the Neoconazole vaccine. It is important to note that if the first day of menstruation is accompanied by menstrual discomfort such as abdominal pain, dizziness, or diarrhea, vaccination is usually not recommended, and you can wait until the discomfort subsides before receiving the New Crown vaccine. If the new crown vaccination is performed in the presence of discomfort symptoms, on the one hand, the vaccination may aggravate the discomfort symptoms and increase the risk; on the other hand, if there is an adverse reaction after vaccination, the condition may be masked, which is not conducive to conducting diagnosis and treatment. Therefore, the decision of whether or not the New Crown vaccination can be given on the first day of menstruation needs to be made after considering a combination of factors such as the individual’s physical condition and symptoms accompanying menstruation. If the vaccination is completed on the first day of menstruation and there are no uncomfortable symptoms, there is no need to worry, as menstruation usually does not affect the vaccine’s function in the body. After vaccination, it is necessary to ensure sufficient rest, keep warm, avoid straining, and keep the injection site clean and dry to avoid local infection, etc.