1.Differences in climate in four seasons, different combinations. In winter, there are more wind-cold, in spring, there are more wind-heat, in summer, there are summer humidity, and in autumn, there are dryness. Therefore, in addition to wind-cold and wind-heat, we should choose the corresponding pungent-warm and pungent-cool relieving drugs, and we should also apply them in combination with summer medicine, damp medicine and moistening medicine according to the differences in the combination of evil. 2, the patient’s physique differences, different combinations. If a deficient person has an external sensation, it is difficult to dispel the surface evil, and according to the different constitutions, they should be used together with deficiency medicines such as qi tonic, yang tonic, yin tonic and blood tonic. Pediatric exopathic, because of the age of the physique and adults are different, and there are different phlegm, stagnation, shock of different concurrent evidence, should also be taken into account, such as cold with phlegm, cough and asthma, with phlegm cough medicine; cold with food, abdominal distension and poor, when with the elimination of drugs; cold with shock, epilepsy night cry, when with the wind and spasm medicine.