Among male genitalia, prepuce and foreskin are more common. Before circumcision, foreskin secretions accumulate under the foreskin to form foreskin scale or foreskin stones, thus triggering infection and inducing local inflammation. In addition, the foreskin in a warm and humid environment is conducive to the survival and reproduction of a variety of microorganisms (including bacteria and viruses, etc.), resulting in the retention of foreskin scale. For men, the chronic stimulation of foreskin scale and recurrent episodes of prepuce head infection are important triggers of penile cancer. Epidemiological studies have shown that the incidence of glansitis and penile cancer in Muslim countries and the Jewish state of Israel, where male circumcision is widely performed, is tens of times lower than that of uncircumcised people, while with circumcision and hypospadias, the incidence of patients will be much higher than normal. It is believed that sexually transmitted pathogens that can cause chronic inflammation of the prostate are associated with the occurrence of prostate cancer, and circumcision can reduce the infection of these pathogens, thus reducing the incidence of prostate cancer. Therefore, circumcision in infancy and preadolescence can effectively prevent the occurrence of glans penis, bungeeitis, encopresis and encopresis, thus reducing the incidence of penile and prostate cancer. Male circumcision can be called the “surgical vaccine” for glans penis. After circumcision, it is easy to maintain genital hygiene, reduce the occurrence of glansitis and urinary tract infections, and also greatly reduce the number of sexually transmitted pathogens through the male genital tract. Studies have proven that circumcision is associated with vulnerability to HIV infection. Circumcision can reduce the rate of HIV infection through vaginal intercourse by 55-76%, and the CDC concluded that circumcision significantly reduces the rate of HIV infection in African men. Some reports also suggest that circumcision or circumcision can also cause cervicitis and even cervical cancer in female sexual partners. Therefore, circumcision can significantly reduce the incidence of these pathogens in the male and female genital tracts and reduce the incidence of cervical cancer in the female partner. In recent years, several large-scale randomized controlled clinical trials have demonstrated that adult male circumcision is effective in reducing the sexual transmission of HIV, HPV and herpes simplex virus type 2. Therefore, we advocate that male circumcision should be promoted as one of the important measures for the prevention of sexually transmitted diseases such as glansitis, penile cancer, and HIV. Male circumcision is not only a “surgical vaccine” for glans, but also a “surgical vaccine” for HIV prevention and reproductive health. However, medical experts have revealed that currently more than 60% of men of age worldwide have not been circumcised. At present, less than 5% of men in China have been circumcised, which means that 95% of men of school age have not been circumcised. The World Health Organization and UNAIDS have published a series of documents on the promotion of male circumcision. Male circumcision is a small, cost-effective, and very safe procedure that only needs to be done once in a lifetime. It is effective not only in the prevention of sexually transmitted diseases such as AIDS, but also in the prevention of urinary tract infections in infants, children and the elderly, the prevention of tumors of the reproductive system and the hygiene of the genitalia of the young.