Diabetic peripheral neuropathy generally refers to diabetic peripheral neuropathy, diabetic peripheral neuropathy is caused by long-term poor glycemic control, it is recommended to actively carry out glucose-lowering treatment, combined with the symptoms of peripheral neuropathy, give anti-oxidative stress treatment, improve microcirculation treatment, nutritional nerve treatment and so on. Diabetic peripheral neuropathy may be caused by high blood glucose or blood glucose fluctuation. In treatment, the key is to control blood sugar, which requires the application of glucose-lowering drugs, such as metformin tablets, insulin, etc., together with the application of anti-oxidative stress drugs, drugs to improve the nerves, and drugs to improve microcirculation, etc., such as lipoic acid capsule, methycobalamin tablets, and prostaglandin injection. In case of severe diabetic peripheral neuropathy, the peripheral nerves of the limbs may have numbness and pain, and pregabalin and gabapentin can be taken to improve the pain symptoms as prescribed by the doctor. Follow your doctor’s instructions when treating with medication. Diabetic patients with peripheral neuropathy must go to a regular hospital for standardized treatment to control blood sugar while treating other complications.