Most patients with hematological diseases require chemotherapeutic drugs, and the osmotic pressure and pH of chemotherapeutic drugs are very irritating to the vessel wall, which can easily produce symptoms of phlebitis such as redness, swelling and pain at the puncture site and vascular localization. Therefore, early deep vein placement is recommended when the peripheral vasculature is not damaged before chemotherapeutic drugs are administered: new technology now allows placement of PICC catheters under ultrasound, increasing the success rate of puncture as well as increasing the choice of puncture sites. Grading of chemotherapeutic phlebitis: Grade I is painful, red and swollen at the puncture site Grade II is painful, red and swollen at the puncture site with striated changes in the vein, no hard nodes palpable Grade III is painful, red and swollen at the puncture site with striated changes in the vein, hard nodes palpable