Clarithromycin extended-release tablets are generally not recommended to be taken for more than 14 consecutive days. Clarithromycin Extended Release can be used for upper and lower respiratory tract infections such as pharyngitis, sinusitis, bronchitis, pneumonia, and mild to moderate infections of the skin and soft tissues. Clarithromycin extended release belongs to the class of antibiotics and the clinical use cycle is usually 7-14 days, the exact number of days of use should depend on the patient’s condition. Also, clarithromycin is mainly excreted by the liver and kidneys, so patients with impaired liver function and renal failure should be cautious when giving clarithromycin extended release. Therefore, clarithromycin extended-release tablets are generally not recommended to be used for more than 2 weeks to avoid adverse reactions, which may affect the metabolism of liver and kidney functions. No contraindication is generally required when taking clarithromycin, but clarithromycin extended-release tablets should not be crushed or chewed and should be swallowed whole to avoid affecting the efficacy of the drug.