There are many causes of macular degeneration in the eyes: the common macular degeneration in young and middle-aged people, mostly seen in central plasmacytoid chorioretinopathy, is caused by a fluid cavity between macular neuroepithelium and pigment epithelium, i.e., shallow retinal detachment; while the more common one in the elderly, considered age-related macular degeneration, may be a large number of vitreous warts in the macular area, or choroidal neovascularization, resulting in macular hemorrhagic edema thus affects vision. Macular fissure is caused by the absence of the whole layer of neuroepithelium in the center of macula, and macular anterior membrane is caused by a layer of proliferating membrane in front of macular retina for various reasons, which will not only affect the vision, but also may pull the retina to cause fissure as well as edema.