Women infected with HPV high risk type 16 is something that must be taken seriously because HPV type 16 infection is very closely related to cervical cancer in women. Therefore, when a woman is tested for HPV type 16 infection, colposcopy and a cervical biopsy at the suspected lesion site must be performed under colposcopic testing. If the colposcopy and cervical biopsy are fine, the patient can be treated with interferon or pessary, and then checked for HPV regularly for 3-6 months. if the patient has persistent HPV16 infection, even if the colposcopy and cervical biopsy are fine, it is recommended that the patient undergo cervical conization to determine if there is intraepithelial neoplasia of the cervix or other parts of the cervix or the development of cervical cancer.