In the 21st century, the danger of obesity in children and adolescents has become the most prominent health problem. In our endocrinology department, 30% of children with severe obesity have fatty liver, and 30-50% of children with fatty liver have abnormal liver function; 80-90% of children with severe obesity have high fasting blood sugar, and 10-20% of them are diagnosed with type 2 diabetes (obese type) in children. About 80% of children’s obesity will be extended to adults, is the adult occurrence of hyperlipidemia, hypertension, coronary heart disease, diabetes, fatty liver cirrhosis and a series of important risk factors, therefore, the prevention and treatment of obese children should cause a high degree of social and family concern. A, how to evaluate pediatric obesity? 1, height – weight method: generally considered that weight more than 20% of its sex height – weight standards for obesity: ≥ 20 ~ 29% for mild obesity; ≥ 30 ~ 39% for moderate obesity; ≥ 40 ~ 59% for severe obesity; ≥ 60% for very severe obesity. 2, body mass index method (BMI): BMI = weight (kg) / height (m2) adult BMI ≥ 25% that is obese; male school-age children BMI ≥ 18%, female school-age children BMI ≥ 17.5% can be diagnosed as obese. Second, what are the causes of obesity? Simple obesity: mostly due to excessive intake of nutrients (95% of obese children like to eat sweets, fried food, addicted to pork, chicken, pasta and other food containing high caloric energy); lack of appropriate physical exercise and too little activity (the United States 70 ~ 80 years of investigation that obesity and watching TV closely related); genetic factors. Pathological obesity: can be secondary to central nervous system diseases, endocrine diseases and hereditary diseases. Common: 1, cortisolism: mostly by the adrenal cortex tumor or hyperplasia, hypothalamus – pituitary tumor; 2, with obesity genetic – endocrine disease: obesity reproductive incompetence syndrome, labor – mon – Bi syndrome, bei – Wei syndrome; 3, other endocrine disease: adrenal cortical hyperplasia, polycystic ovary syndrome, etc.. Third, what are the hazards of obesity? 1, obesity seriously affects the physical and mental health of children, obese children are often afraid of being ridiculed, and reluctant to interact with other children, often have psychological barriers, such as low self-esteem, timidity, loneliness, etc.; 2, obese children often have early sexual development, and the level of growth hormone secretion is low, so the final height is often lower than normal children; 3, obesity can lead to sex hormone secretion disorders, men can cause low sexual function, impotence, women can cause 4, for children who are growing, obesity can affect the function of parathyroid hormone and vitamin D metabolic disorders, resulting in rickets; 5, obesity will also cause serious multi-system diseases such as: hypertension, heart disease, lipid metabolism disorders, fatty liver, cholelithiasis, hyperinsulinemia, type 2 diabetes, etc.; 6, obesity can also inhibit the body’s immune function, prone to respiratory 7, with obesity genetic – endocrine diseases often with obesity, mental retardation, gonadal dysplasia, visual impairment, etc. as the main performance. Fourth, children’s obesity should not be ignored based on obesity has the above hazards, so the prevention of childhood obesity is particularly important, should also pay attention to the prevention and treatment of children’s hypertension, heart disease, diabetes, especially for children with a family history of the above diseases should be regularly measured blood pressure, blood lipids, glucose tolerance test, blood sugar, insulin, C peptide, cortisol and other endocrine checks, timely detection of disease and timely treatment, the disease is controlled in the The disease should be detected and treated in time to control the disease in the bud.