Drug-induced kidney injury is possible to be self-healed, the specific situation needs to be combined with the actual severity of the injury, whether it can be self-healed is related to the type of drugs and the use of time, the degree of damage to kidney function and other factors. Because each person’s physical quality is different, the degree of damage is different, the recovery situation is different, so there are individual differences. If the kidney injury is caused by osmotic diuretics such as mannitol, there is a certain possibility of self-healing, but if it is interstitial kidney damage caused by long-term use of non-steroidal anti-inflammatory drugs, it is very difficult to self-heal to a normal state. If the drug-induced kidney damage is not very serious in the early stage, it can usually recover by itself after a period of time after stopping the drug. If the kidney damage is not noticed and the medication is taken for too long, it may cause irreversible kidney damage, which is generally irrecoverable. If you encounter drug-related kidney injury, you should consult the doctor in time and take standardized treatment under the doctor’s guidance, and do not use medicines and health care products indiscriminately, so as not to miss the opportunity of the disease.