Café-au-lait Spots, also known by the technical term Café-au-lait Spots, the cause of which is not well understood, has an incidence of about 10-20% in the population. Most of them are only a kind of pigmented skin damage, but a few of them can occur in combination with systemic diseases such as multiple neurofibromatosis, tuberous sclerosis or Albright syndrome. (1) The skin lesion characteristics: (1) at birth or from early childhood. (2) Can occur in any part of the body. (3) Most of them are light brown spots of several millimeters to several centimeters in size, with regular edges, different shapes and smooth surfaces. Note: If 6 or more café au lait spots larger than 1.5cm in diameter appear on the baby’s skin (the diameter of prepubertal patients is larger than 0.5cm), parents should bring the child to the clinic, except for the possibility of combined neurofibromatosis if necessary. For aesthetic reasons, 510nm pulsed dye laser, 532nm frequency doubled Nd:YAG laser, 694nm Q-switched ruby laser or 755nm Q-switched emerald laser can be used for “blackening” laser treatment.