There are many ways to remove wrinkles in today’s society. The traditional surgery to remove wrinkles has been widely recognized, and the surgery has also developed from simple excision to tighten the skin to SMAS fascia suspension and deep wrinkle removal on the periosteum. However, some patients can not accept the scar left after the surgery, and the surgery also requires a certain period of recovery. With the rapid development of science and technology, a number of advanced plastic cosmetic methods came into being, the following is an introduction to several methods of wrinkle removal: 1, minimally invasive small incision wrinkle removal: it is the use of small incision instruments, in the hair within the tiny incision to complete the surgery, its small incision, small damage, widely accepted by patients, endoscopic technology also belongs to a small incision wrinkle removal, forehead wrinkles and wrinkles between the eyebrows nasal transverse wrinkles treatment effect is obvious; 2, Botulinum toxin injection for wrinkle removal: according to different types of facial wrinkles and the mechanism of botulinum toxin’s action, it has obvious treatment effect for power wrinkles (forehead wrinkles, inter-brow wrinkles, nasal wrinkles, crow’s feet, and lower eye bag wrinkles), and at the same time, botulinum toxin can also be used to treat face slimming, calf slimming, and comprehensive treatment of scarring; 3. Biological filler wrinkles removal: after the national regular authentication, there are hyaluronic acid and collagen, and it can achieve wrinkle removal purpose through subcutaneous filler, and can treat wrinkle removal. To achieve the purpose of wrinkle removal, can be treated in addition to most of the wrinkles around the eyes outside; 4, laser, photon skin rejuvenation wrinkle: the use of laser and photon photothermal effect of the principle of stimulating subcutaneous collagen proliferation and rearrangement, so that the dermis layer becomes thicker, to achieve the purpose of removing wrinkles.