Once adolescents have chest tightness and shortness of breath, there may be several causes: 1) pleurisy; 2) costochondritis; 3) infection of the lungs; 4) cardiac neurosis. Generally, when this happens in teenagers, it is more often the case of cardiac neurosis, which is also called neurosis, a term that has been proposed in recent years. It is in doing any examination, such as electrocardiogram, cardiac ultrasound, coronary CT, etc. are not seen to have organic lesions, and the patient will always feel, such as chest tightness, shortness of breath, dizziness, palpitations, etc., is a state of neurosis. This condition can be treated with glutathione and vitamin B12 for regulation of nerves.