Cone keratoconus is a type of disease characterized by dilatation of the cornea, resulting in a cone-like protrusion of the central cornea, a high degree of astigmatism, and ultimately a severe impact on vision. The disease is mostly seen in young people and develops in both eyes. In the early stage, the disease is insidious and not easily detected, mainly manifesting as refractive error. However, as the disease progresses, vision decreases further, and it is difficult to correct with glasses. At this point, only corneal contact lenses, i.e. contact lenses, can be worn to correct the problem. As the disease continues to progress, there is no way to wear corneal contact lenses because of the obvious corneal protrusion, and at this time, vision is mostly poor and scarring appears in the center of the cornea, which is an indication for corneal transplantation. For those with good conditions and no obvious corneal scar, deep lamellar corneal transplantation can be considered, while for those with poor conditions and obvious corneal scar, only penetrating corneal transplantation can be done. The postoperative rejection of corneal transplantation for conical corneas is relatively low compared to corneal transplantation for other corneal diseases, and the prognosis is relatively good.