Slow heart rate and premature beats may be caused by physiological factors such as long-term exercise, or they may be related to pathological causes such as hypothyroidism and coronary atherosclerosis, and different medications can be taken to alleviate the symptoms according to the causes. 1. Physiological factors: generally seen in young people or athletes, mainly due to the heart’s single pacing volume is more, even if the heart rate is relatively slow, can meet the heart’s blood supply, this physiological slow heart rate, premature beats generally do not need special treatment. 2. Pathologic causes: (1) Hypothyroidism: also known as hypothyroidism, when there is a decrease in thyroid hormones, it may affect the normal blood supply to the heart, thus causing a slow heart rate. Supplementation of levothyroxine tablets is now required, which can maintain growth and development and prompt the body to restore normal metabolism. (2) Coronary atherosclerotic heart disease: that is, coronary heart disease, when the seriousness of the disease leads to the narrowing of the blood vessel lumen or obstruction, affecting the normal blood supply to the heart muscle, oxygen supply, may cause the heart rate to slow down, inducing premature beats. For this disease need to insist on taking nitroglycerin, isosorbide nitrate, mainly through the inhibition of platelet aggregation and adhesion to achieve the therapeutic purpose, can promote coronary artery expansion. Slow heart rate and premature beats, it is recommended to consult a doctor, and under the guidance of a professional physician for electrocardiogram, dynamic electrocardiogram, cardiac ultrasound examination to analyze the cause of the disease, and then according to the diagnostic results of targeted treatment.