It is an irresistible fact that as we age, the face ages and various wrinkles appear. With the development of cosmetic technology, in addition to surgical wrinkle removal, non-surgical wrinkle removal has also made great progress. We generally divide facial wrinkles into head lines, frowning Kawasaki lines, crow’s feet at the outer corners of the eyes, nasolabial folds above the corners of the mouth (also known as the decree line), and horizontal neck lines on the neck. These wrinkles can appear at rest (i.e., when the face is expressionless), or they can appear or worsen when they are dynamic (e.g., frowning, smiling, etc.). The removal of dynamic wrinkles can be solved by injecting Botulinum toxin type A. For example, an injection in the frown muscle can paralyze it to the point of not being able to frown, thus eliminating the wrinkles. The effect of Botox injection lasts for about 6 months and can be repeated. The removal of static wrinkles can be solved by applying Restylane 2 (hyaluronic acid dermal filler, called hyaluronic acid in Hong Kong). In common parlance, it is used to fill in and smooth out the static wrinkles. The effect of one injection of Restylane 2 can be maintained for about 1 year and can be repeatedly injected. Special Note: All of the above treatments should be performed in a hospital with medical aesthetic qualification. At present, there are many kinds of hyaluronic acid brands in the market, which are very confusing, but there is only one kind of “Ruilan” from Sweden that is really approved by the Chinese Food and Drug Administration. Botox is a toxic drug strictly managed by the state because it is highly toxic. It is safe to be injected by a professional doctor with medical qualification through regular channels.