The biggest possibility for your boyfriend to urinate a lot at night is prostatitis. When the prostate is inflamed, the prostate is congested and edematous, and you will have excessive nighttime urination and frequent urination. The best way is to take oral alpha-blockers, commonly used drugs such as Halo, Alfuzosin, Terazosin, Doxazosin, one oral tablet every night before bed. Warm sitz baths are recommended every night to promote symptom relief and absorption of inflammation. Don’t stay long, don’t masturbate or have sexual intercourse frequently, discharge prostate fluid and semen regularly. The actual fact is that you can find a lot more than just a few of these. You should have your prostate fluid tested to see the severity of prostatitis. If the inflammation is heavy, you can increase the antimicrobial oral, antimicrobial recommended clarithromycin.