1, Patients with blood in the stool, either fresh blood, dark red, or black old bleeding. 2.Patients with bleeding and painful bowel movements, especially patients with recurrent episodes of blood in the stool with pain. 3.Patients who have a swelling coming out of the anus after defecation and even need help to stuff it back by hand. 4.Patients who have a flab outside the anus that cannot be wiped clean after the stool. 5.Patients with repeated anal dampness and perianal itching. 6.Patients who have had anal intercourse and have small meatus at the edge of the anus. 7.Patients with change in bowel habits,. 8.Patients with painful swelling on the anal side. 9.Anal pimples that never heal. 10.Patients who always have pain in the anal crevice and have a breakout and a lot of body hair. 11.Patients with anal swelling and discomfort, always feel like defecating, but defecation does not come out, or only a small amount of stool is discharged.