Causes of acute pancreatitis include: biliary tract diseases, alcohol consumption, metabolic diseases, duodenal fluid reflux and others. 1. Biliary tract diseases: accounting for more than 50% of the cases, it is called biliary pancreatitis. The main causes are gallstones, gallbladder surgery, biliary tract inflammation and biliary roundworms. 2. Alcohol consumption: one of the common causes, ethanol can damage the pancreas, leading to rupture of the pancreatic duct, inducing acute pancreatitis. 3. Metabolic diseases: such as hyperlipidemia and hypercalcemia can trigger acute pancreatitis. 4. Duodenal reflux: Duodenal reflux into the pancreas can also trigger acute pancreatitis. The main causes of reflux are duodenal diverticulum and obstruction of input collaterals after major gastrectomy. 5. Other: medical factors, such as endoscopic retrograde cholangiopancreatography; tumors, such as pancreatic cancer; drugs, such as azathioprine, metronidazole, etc.; trauma, such as epigastric blunt force trauma, surgical trauma, etc. can lead to acute pancreatitis attacks. Therefore, there are more causes of acute pancreatitis, and patients should consult the doctor in time and get treatment as early as possible to avoid delaying the condition and affecting the prognosis.