Stomach bloating after H. pylori infection is mainly due to the clinical manifestations of H. pylori infection, so eradication of H. pylori will relieve stomach bloating. The current regimen used to kill H. pylori is a quadruple regimen, including acid suppressants, bismuth and two antibiotics. The antibiotics can be chosen among metronidazole, clarithromycin, tetracycline, amoxicillin and levofloxacin, among which amoxicillin and tetracycline are the more sensitive antibiotics, but they should be chosen in conjunction with whether the patient has a history of drug allergy and whether he or she has a history of taking them in the past. Each antibiotic has adverse reactions. Metronidazole can cause nausea, vomiting and other gastrointestinal symptoms, while clarithromycin may cause heartburn. Clarithromycin, metronidazole and levofloxacin all have high resistance rates, so you should still try to choose a sensitive antibiotic when killing H. pylori. For gastric distention after infection with H. pylori, taking medication mainly to kill H. pylori can effectively relieve gastric distention.